Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Mania
ADR ID BADD_A02660
ADR Hierarchy
19      Psychiatric disorders
19.16      Manic and bipolar mood disorders and disturbances
19.16.02      Mood alterations with manic symptoms
19.16.02.002      Mania
Description A disorder characterized by excitement of psychotic proportions manifested by mental and physical hyperactivity, disorganization of behavior and elevation of mood. [CTCAE] A major affective disorder marked by severe mood swings (manic or major depressive episodes) and a tendency to remission and recurrence. [MeSH]
MedDRA Code 10026749
MeSH ID D001714; D001714; D001714
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Acute mania | Atypical manic disorder | Change to manic state | Mania | Mania acute | Mania aggravated | Manic | Manic disorder, recurrent episode | Manic disorder, recurrent episode, in full remission | Manic disorder, recurrent episode, in partial or unspecified remission | Manic disorder, recurrent episode, mild degree | Manic disorder, recurrent episode, moderate degree | Manic disorder, recurrent episode, severe degree, specified as with psychotic behavior | Manic disorder, recurrent episode, severe degree, specified as with psychotic behaviour | Manic disorder, recurrent episode, severe degree, without mention psychotic behavior | Manic disorder, recurrent episode, severe degree, without mention psychotic behaviour | Manic disorder, recurrent episode, unspecified degree | Manic disorder, single episode | Manic disorder, single episode, in full remission | Manic disorder, single episode, in partial or unspecified remission | Manic disorder, single episode, mild degree | Manic disorder, single episode, moderate degree | Manic disorder, single episode, severe degree, specified as with psychotic behavior | Manic disorder, single episode, severe degree, specified as with psychotic behaviour | Manic disorder, single episode, severe degree, without mention of psychotic behavior | Manic disorder, single episode, unspecified degree | Manic episode | Manic excitement | Manic psychosis | Manic reaction | Manic state | Manic state aggravated | Oppression to conduct act | Psychosis manic | Reaction manic | Bipolar Disorder | Bipolar Disorders | Disorder, Bipolar | Psychosis, Manic-Depressive | Psychosis, Manic Depressive | Manic-Depressive Psychosis | Manic Depressive Psychosis | Affective Psychosis, Bipolar | Bipolar Affective Psychosis | Psychoses, Bipolar Affective | Psychosis, Bipolar Affective | Psychoses, Manic-Depressive | Manic-Depressive Psychoses | Psychoses, Manic Depressive | Manias | Manic State | Manic States | State, Manic | States, Manic | Depression, Bipolar | Bipolar Depression | Manic Disorder | Disorder, Manic | Manic Disorders
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Not AvailableNot AvailableNot Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D01309Lomefloxacin--
BADD_D01318Lorazepam0.000403%
BADD_D01330Lurasidone0.007166%
BADD_D01350Maprotiline--
BADD_D01351Maprotiline hydrochloride--
BADD_D01366Medroxyprogesterone acetate0.000511%
BADD_D01378Memantine0.001153%
BADD_D01431Methylphenidate0.001377%
BADD_D01433Methylprednisolone--
BADD_D01434Methylprednisolone acetate--
BADD_D01435Methylprednisolone hemisuccinate0.020984%
BADD_D01442Metoclopramide--
BADD_D01476Mirtazapine0.002371%
BADD_D01484Modafinil--
BADD_D01496Montelukast0.000104%
BADD_D01498Morphine--
BADD_D01507Mycophenolate mofetil--
BADD_D01588Nortriptyline--
BADD_D01598Ofloxacin--
BADD_D01599Olanzapine0.020020%
BADD_D01637Oxcarbazepine0.000831%
BADD_D01645Oxycodone0.000232%
BADD_D01654Palbociclib--
BADD_D01656Paliperidone0.159642%
BADD_D01679Paroxetine0.001028%
BADD_D01680Paroxetine hydrochloride--
BADD_D01681Paroxetine hydrochloride hemihydrate--
BADD_D01682Paroxetine impurity a--
BADD_D01683Paroxetine mesylate--
BADD_D01735Pergolide--
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